Prognostic impact of reduced connexin43 expression and gap junction coupling of neoplastic stromal c...
Prognostic impact of reduced connexin43 expression and gap junction coupling of neoplastic stromal cells in giant cell tumor of bone
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Missense mutations of the GJA1 gene encoding the gap junction channel protein connexin43 (Cx43) cause bone malformations resulting in oculodentodigital dysplasia (ODDD), while GJA1 null and ODDD mutant mice develop osteopenia. In this study we investigated Cx43 expression and channel functions in giant cell tumor of bone (GCTB), a locally aggressiv...
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Full title
Prognostic impact of reduced connexin43 expression and gap junction coupling of neoplastic stromal cells in giant cell tumor of bone
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TN_cdi_plos_journals_1677644986
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1677644986
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0125316
