HYS-32-Induced Microtubule Catastrophes in Rat Astrocytes Involves the PI3K-GSK3beta Signaling Pathw...
HYS-32-Induced Microtubule Catastrophes in Rat Astrocytes Involves the PI3K-GSK3beta Signaling Pathway
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United States: Public Library of Science
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English
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United States: Public Library of Science
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HYS-32 is a novel derivative of combretastatin-A4 (CA-4) previously shown to induce microtubule coiling in rat primary astrocytes. In this study, we further investigated the signaling mechanism and EB1, a microtubule-associated end binding protein, involved in HYS-32-induced microtubule catastrophes. Confocal microscopy with double immunofluorescen...
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HYS-32-Induced Microtubule Catastrophes in Rat Astrocytes Involves the PI3K-GSK3beta Signaling Pathway
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TN_cdi_plos_journals_1678577759
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1678577759
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1932-6203
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1932-6203
DOI
10.1371/journal.pone.0126217