IL-11 Attenuates Liver Ischemia/Reperfusion Injury (IRI) through STAT3 Signaling Pathway in Mice
IL-11 Attenuates Liver Ischemia/Reperfusion Injury (IRI) through STAT3 Signaling Pathway in Mice
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Author / Creator
Zhu, Miao , Lu, Bo , Cao, Qinhong , Wu, Zhenfeng , Xu, Zhe , Li, Weisu , Yao, Xuequan and Liu, Fukun
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
The protective role of IL-11, an IL-6 family cytokine, has been implicated in ischemia/reperfusion injury (IRI) in the heart and kidney, but its role has not been elucidated in liver IRI. This study was designed to evaluate the effects of IL-11 and its mechanism of action on liver IRI in a mouse model.
A partial (70%) warm liver IRI was induced...
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Full title
IL-11 Attenuates Liver Ischemia/Reperfusion Injury (IRI) through STAT3 Signaling Pathway in Mice
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TN_cdi_plos_journals_1679179164
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1679179164
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0126296