The Longitudinal Transcriptomic Response of the Substantia Nigra to Intrastriatal 6-Hydroxydopamine...
The Longitudinal Transcriptomic Response of the Substantia Nigra to Intrastriatal 6-Hydroxydopamine Reveals Significant Upregulation of Regeneration-Associated Genes
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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We hypothesized that the study of gene expression at 1, 2, 4, 6 and 16 weeks in the substantia nigra (SN) after intrastriatal 6-OHDA in the Sprague-Dawley rat (rattus norvegicus) would identify cellular responses during the degenerative process that could be axoprotective. Specifically, we hypothesized that genes expressed within the SN that follow...
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Full title
The Longitudinal Transcriptomic Response of the Substantia Nigra to Intrastriatal 6-Hydroxydopamine Reveals Significant Upregulation of Regeneration-Associated Genes
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TN_cdi_plos_journals_1682209865
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1682209865
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0127768
