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Systemic Monocytic-MDSCs Are Generated from Monocytes and Correlate with Disease Progression in Brea...

Systemic Monocytic-MDSCs Are Generated from Monocytes and Correlate with Disease Progression in Brea...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1682211711

Systemic Monocytic-MDSCs Are Generated from Monocytes and Correlate with Disease Progression in Breast Cancer Patients

About this item

Full title

Systemic Monocytic-MDSCs Are Generated from Monocytes and Correlate with Disease Progression in Breast Cancer Patients

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-05, Vol.10 (5), p.e0127028

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Myeloid-derived suppressor cells (MDSCs) are highly immunosuppressive myeloid cells, which increase in cancer patients. The molecular mechanism behind their generation and function is unclear. Whereas granulocytic-MDSCs correlate with poor overall survival in breast cancer, the presence and relevance of monocytic-MDSCs (Mo-MDSCs) is unknown. Here w...

Alternative Titles

Full title

Systemic Monocytic-MDSCs Are Generated from Monocytes and Correlate with Disease Progression in Breast Cancer Patients

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1682211711

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1682211711

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0127028

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