Monosodium Urate Crystals Promote Innate Anti-Mycobacterial Immunity and Improve BCG Efficacy as a V...
Monosodium Urate Crystals Promote Innate Anti-Mycobacterial Immunity and Improve BCG Efficacy as a Vaccine against Tuberculosis
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
A safer and more effective anti-Tuberculosis vaccine is still an urgent need. We probed the effects of monosodium urate crystals (MSU) on innate immunity to improve the Bacille Calmette-Guerin (BCG) vaccination. Results showed that in vitro MSU cause an enduring macrophage stimulation of the anti-mycobacterial response, measured as intracellular ki...
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Full title
Monosodium Urate Crystals Promote Innate Anti-Mycobacterial Immunity and Improve BCG Efficacy as a Vaccine against Tuberculosis
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TN_cdi_plos_journals_1684191921
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1684191921
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0127279
