PI3K Signaling and Stat92E Converge to Modulate Glial Responsiveness to Axonal Injury
PI3K Signaling and Stat92E Converge to Modulate Glial Responsiveness to Axonal Injury
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Contents
Glial cells are exquisitely sensitive to neuronal injury but mechanisms by which glia establish competence to respond to injury, continuously gauge neuronal health, and rapidly activate reactive responses remain poorly defined. Here, we show glial PI3K signaling in the uninjured brain regulates baseline levels of Draper, a receptor essential for Dr...
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PI3K Signaling and Stat92E Converge to Modulate Glial Responsiveness to Axonal Injury
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TN_cdi_plos_journals_1685009582
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1685009582
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ISSN
1545-7885,1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.1001985
