Dynamic Modelling of Pathways to Cellular Senescence Reveals Strategies for Targeted Interventions
Dynamic Modelling of Pathways to Cellular Senescence Reveals Strategies for Targeted Interventions
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Cellular senescence, a state of irreversible cell cycle arrest, is thought to help protect an organism from cancer, yet also contributes to ageing. The changes which occur in senescence are controlled by networks of multiple signalling and feedback pathways at the cellular level, and the interplay between these is difficult to predict and understan...
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Dynamic Modelling of Pathways to Cellular Senescence Reveals Strategies for Targeted Interventions
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TN_cdi_plos_journals_1685029871
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1685029871
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ISSN
1553-7358,1553-734X
E-ISSN
1553-7358
DOI
10.1371/journal.pcbi.1003728
