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Phase transitions in the multi-cellular regulatory behavior of pancreatic islet excitability

Phase transitions in the multi-cellular regulatory behavior of pancreatic islet excitability

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1685030994

Phase transitions in the multi-cellular regulatory behavior of pancreatic islet excitability

About this item

Full title

Phase transitions in the multi-cellular regulatory behavior of pancreatic islet excitability

Publisher

United States: Public Library of Science

Journal title

PLoS computational biology, 2014-09, Vol.10 (9), p.e1003819-e1003819

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The pancreatic islets of Langerhans are multicellular micro-organs integral to maintaining glucose homeostasis through secretion of the hormone insulin. β-cells within the islet exist as a highly coupled electrical network which coordinates electrical activity and insulin release at high glucose, but leads to global suppression at basal glucose. De...

Alternative Titles

Full title

Phase transitions in the multi-cellular regulatory behavior of pancreatic islet excitability

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1685030994

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1685030994

Other Identifiers

ISSN

1553-7358,1553-734X

E-ISSN

1553-7358

DOI

10.1371/journal.pcbi.1003819

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