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SteatoNet: The First Integrated Human Metabolic Model with Multi-layered Regulation to Investigate L...

SteatoNet: The First Integrated Human Metabolic Model with Multi-layered Regulation to Investigate L...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1685035427

SteatoNet: The First Integrated Human Metabolic Model with Multi-layered Regulation to Investigate Liver-Associated Pathologies

About this item

Full title

SteatoNet: The First Integrated Human Metabolic Model with Multi-layered Regulation to Investigate Liver-Associated Pathologies

Publisher

United States: Public Library of Science

Journal title

PLoS computational biology, 2014-12, Vol.10 (12), p.e1003993-e1003993

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Current state-of-the-art mathematical models to investigate complex biological processes, in particular liver-associated pathologies, have limited expansiveness, flexibility, representation of integrated regulation and rely on the availability of detailed kinetic data. We generated the SteatoNet, a multi-pathway, multi-tissue model and in silico pl...

Alternative Titles

Full title

SteatoNet: The First Integrated Human Metabolic Model with Multi-layered Regulation to Investigate Liver-Associated Pathologies

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1685035427

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1685035427

Other Identifiers

ISSN

1553-7358,1553-734X

E-ISSN

1553-7358

DOI

10.1371/journal.pcbi.1003993

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