Comprehensive Sieve Analysis of Breakthrough HIV-1 Sequences in the RV144 Vaccine Efficacy Trial
Comprehensive Sieve Analysis of Breakthrough HIV-1 Sequences in the RV144 Vaccine Efficacy Trial
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Author / Creator
Edlefsen, Paul T. , Rolland, Morgane , Hertz, Tomer , Tovanabutra, Sodsai , Gartland, Andrew J. , deCamp, Allan C. , Magaret, Craig A. , Ahmed, Hasan , Gottardo, Raphael , Juraska, Michal , McCoy, Connor , Larsen, Brendan B. , Sanders-Buell, Eric , Carrico, Chris , Menis, Sergey , Bose, Meera , Arroyo, Miguel A. , O’Connell, Robert J. , Nitayaphan, Sorachai , Pitisuttithum, Punnee , Kaewkungwal, Jaranit , Rerks-Ngarm, Supachai , Robb, Merlin L. , Kirys, Tatsiana , Georgiev, Ivelin S. , Kwong, Peter D. , Scheffler, Konrad , Pond, Sergei L. Kosakovsky , Carlson, Jonathan M. , Michael, Nelson L. , Schief, William R. , Mullins, James I. , Kim, Jerome H. , Gilbert, Peter B. and RV144 Sequencing Team
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
The RV144 clinical trial showed the partial efficacy of a vaccine regimen with an estimated vaccine efficacy (VE) of 31% for protecting low-risk Thai volunteers against acquisition of HIV-1. The impact of vaccine-induced immune responses can be investigated through sieve analysis of HIV-1 breakthrough infections (infected vaccine and placebo recipi...
Alternative Titles
Full title
Comprehensive Sieve Analysis of Breakthrough HIV-1 Sequences in the RV144 Vaccine Efficacy Trial
Authors, Artists and Contributors
Author / Creator
Rolland, Morgane
Hertz, Tomer
Tovanabutra, Sodsai
Gartland, Andrew J.
deCamp, Allan C.
Magaret, Craig A.
Ahmed, Hasan
Gottardo, Raphael
Juraska, Michal
McCoy, Connor
Larsen, Brendan B.
Sanders-Buell, Eric
Carrico, Chris
Menis, Sergey
Bose, Meera
Arroyo, Miguel A.
O’Connell, Robert J.
Nitayaphan, Sorachai
Pitisuttithum, Punnee
Kaewkungwal, Jaranit
Rerks-Ngarm, Supachai
Robb, Merlin L.
Kirys, Tatsiana
Georgiev, Ivelin S.
Kwong, Peter D.
Scheffler, Konrad
Pond, Sergei L. Kosakovsky
Carlson, Jonathan M.
Michael, Nelson L.
Schief, William R.
Mullins, James I.
Kim, Jerome H.
Gilbert, Peter B.
RV144 Sequencing Team
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1685048272
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1685048272
Other Identifiers
ISSN
1553-7358,1553-734X
E-ISSN
1553-7358
DOI
10.1371/journal.pcbi.1003973