Genome Wide Association Identifies Common Variants at the SERPINA6/SERPINA1 Locus Influencing Plasma...
Genome Wide Association Identifies Common Variants at the SERPINA6/SERPINA1 Locus Influencing Plasma Cortisol and Corticosteroid Binding Globulin
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Author / Creator
Bolton, Jennifer L. , Hayward, Caroline , Direk, Nese , Lewis, John G. , Hammond, Geoffrey L. , Hill, Lesley A. , Anderson, Anna , Huffman, Jennifer , Wilson, James F. , Campbell, Harry , Rudan, Igor , Wright, Alan , Hastie, Nicholas , Wild, Sarah H. , Velders, Fleur P. , Hofman, Albert , Uitterlinden, Andre G. , Lahti, Jari , Räikkönen, Katri , Kajantie, Eero , Widen, Elisabeth , Palotie, Aarno , Eriksson, Johan G. , Kaakinen, Marika , Järvelin, Marjo-Riitta , Timpson, Nicholas J. , Davey Smith, George , Ring, Susan M. , Evans, David M. , St Pourcain, Beate , Tanaka, Toshiko , Milaneschi, Yuri , Bandinelli, Stefania , Ferrucci, Luigi , van der Harst, Pim , Rosmalen, Judith G. M. , Bakker, Stephen J. L. , Verweij, Niek , Dullaart, Robin P. F. , Mahajan, Anubha , Lindgren, Cecilia M. , Morris, Andrew , Lind, Lars , Ingelsson, Erik , Anderson, Laura N. , Pennell, Craig E. , Lye, Stephen J. , Matthews, Stephen G. , Eriksson, Joel , Mellstrom, Dan , Ohlsson, Claes , Price, Jackie F. , Strachan, Mark W. J. , Reynolds, Rebecca M. , Tiemeier, Henning , Walker, Brian R. , on behalf of the CORtisol NETwork (CORNET) Consortium and CORtisol NETwork (CORNET) Consortium
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Variation in plasma levels of cortisol, an essential hormone in the stress response, is associated in population-based studies with cardio-metabolic, inflammatory and neuro-cognitive traits and diseases. Heritability of plasma cortisol is estimated at 30-60% but no common genetic contribution has been identified. The CORtisol NETwork (CORNET) conso...
Alternative Titles
Full title
Genome Wide Association Identifies Common Variants at the SERPINA6/SERPINA1 Locus Influencing Plasma Cortisol and Corticosteroid Binding Globulin
Authors, Artists and Contributors
Author / Creator
Hayward, Caroline
Direk, Nese
Lewis, John G.
Hammond, Geoffrey L.
Hill, Lesley A.
Anderson, Anna
Huffman, Jennifer
Wilson, James F.
Campbell, Harry
Rudan, Igor
Wright, Alan
Hastie, Nicholas
Wild, Sarah H.
Velders, Fleur P.
Hofman, Albert
Uitterlinden, Andre G.
Lahti, Jari
Räikkönen, Katri
Kajantie, Eero
Widen, Elisabeth
Palotie, Aarno
Eriksson, Johan G.
Kaakinen, Marika
Järvelin, Marjo-Riitta
Timpson, Nicholas J.
Davey Smith, George
Ring, Susan M.
Evans, David M.
St Pourcain, Beate
Tanaka, Toshiko
Milaneschi, Yuri
Bandinelli, Stefania
Ferrucci, Luigi
van der Harst, Pim
Rosmalen, Judith G. M.
Bakker, Stephen J. L.
Verweij, Niek
Dullaart, Robin P. F.
Mahajan, Anubha
Lindgren, Cecilia M.
Morris, Andrew
Lind, Lars
Ingelsson, Erik
Anderson, Laura N.
Pennell, Craig E.
Lye, Stephen J.
Matthews, Stephen G.
Eriksson, Joel
Mellstrom, Dan
Ohlsson, Claes
Price, Jackie F.
Strachan, Mark W. J.
Reynolds, Rebecca M.
Tiemeier, Henning
Walker, Brian R.
on behalf of the CORtisol NETwork (CORNET) Consortium
CORtisol NETwork (CORNET) Consortium
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1685087652
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1685087652
Other Identifiers
ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1004474