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ssb Gene Duplication Restores the Viability of [delta] holC and [delta] holD Escherichia coli Mutant...

ssb Gene Duplication Restores the Viability of [delta] holC and [delta] holD Escherichia coli Mutant...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1685129975

ssb Gene Duplication Restores the Viability of [delta] holC and [delta] holD Escherichia coli Mutants

About this item

Full title

ssb Gene Duplication Restores the Viability of [delta] holC and [delta] holD Escherichia coli Mutants

Publisher

Public Library of Science

Journal title

PLoS genetics, 2014-10, Vol.10 (10)

Language

English

Formats

Publication information

Publisher

Public Library of Science

More information

Scope and Contents

Contents

 
The HolC-HolD (χψ) complex is part of the DNA polymerase III holoenzyme (Pol III HE) clamp-loader. Several lines of evidence indicate that both leading- and lagging-strand synthesis are affected in the absence of this complex. The Escherichia coli δholD mutant grows poorly and suppressor mutations that restore growth appear spontaneously. Here...

Alternative Titles

Full title

ssb Gene Duplication Restores the Viability of [delta] holC and [delta] holD Escherichia coli Mutants

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1685129975

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1685129975

Other Identifiers

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1004719

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