Inactivation of PNKP by Mutant ATXN3 Triggers Apoptosis by Activating the DNA Damage-Response Pathwa...
Inactivation of PNKP by Mutant ATXN3 Triggers Apoptosis by Activating the DNA Damage-Response Pathway in SCA3
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Spinocerebellar ataxia type 3 (SCA3), also known as Machado-Joseph disease (MJD), is an untreatable autosomal dominant neurodegenerative disease, and the most common such inherited ataxia worldwide. The mutation in SCA3 is the expansion of a polymorphic CAG tri-nucleotide repeat sequence in the C-terminal coding region of the ATXN3 gene at chromoso...
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Inactivation of PNKP by Mutant ATXN3 Triggers Apoptosis by Activating the DNA Damage-Response Pathway in SCA3
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TN_cdi_plos_journals_1685137366
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1685137366
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1553-7404,1553-7390
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1553-7404
DOI
10.1371/journal.pgen.1004834
