Mitochondrial dysfunction reveals the role of mRNA poly(A) tail regulation in oculopharyngeal muscul...
Mitochondrial dysfunction reveals the role of mRNA poly(A) tail regulation in oculopharyngeal muscular dystrophy pathogenesis
About this item
Full title
Author / Creator
Chartier, Aymeric , Klein, Pierre , Pierson, Stéphanie , Barbezier, Nicolas , Gidaro, Teresa , Casas, François , Carberry, Steven , Dowling, Paul , Maynadier, Laurie , Bellec, Maëlle , Oloko, Martine , Jardel, Claude , Moritz, Bodo , Dickson, George , Mouly, Vincent , Ohlendieck, Kay , Butler-Browne, Gillian , Trollet, Capucine and Simonelig, Martine
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Oculopharyngeal muscular dystrophy (OPMD), a late-onset disorder characterized by progressive degeneration of specific muscles, results from the extension of a polyalanine tract in poly(A) binding protein nuclear 1 (PABPN1). While the roles of PABPN1 in nuclear polyadenylation and regulation of alternative poly(A) site choice are established, the m...
Alternative Titles
Full title
Mitochondrial dysfunction reveals the role of mRNA poly(A) tail regulation in oculopharyngeal muscular dystrophy pathogenesis
Authors, Artists and Contributors
Author / Creator
Klein, Pierre
Pierson, Stéphanie
Barbezier, Nicolas
Gidaro, Teresa
Casas, François
Carberry, Steven
Dowling, Paul
Maynadier, Laurie
Bellec, Maëlle
Oloko, Martine
Jardel, Claude
Moritz, Bodo
Dickson, George
Mouly, Vincent
Ohlendieck, Kay
Butler-Browne, Gillian
Trollet, Capucine
Simonelig, Martine
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1685140299
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1685140299
Other Identifiers
ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1005092
