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Synergistic Interactions between Drosophila Orthologues of Genes Spanned by De Novo Human CNVs Suppo...

Synergistic Interactions between Drosophila Orthologues of Genes Spanned by De Novo Human CNVs Suppo...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1685141274

Synergistic Interactions between Drosophila Orthologues of Genes Spanned by De Novo Human CNVs Support Multiple-Hit Models of Autism

About this item

Full title

Synergistic Interactions between Drosophila Orthologues of Genes Spanned by De Novo Human CNVs Support Multiple-Hit Models of Autism

Publisher

United States: Public Library of Science

Journal title

PLoS genetics, 2015-03, Vol.11 (3), p.e1004998-e1004998

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Autism spectrum disorders (ASDs) are highly heritable and characterised by deficits in social interaction and communication, as well as restricted and repetitive behaviours. Although a number of highly penetrant ASD gene variants have been identified, there is growing evidence to support a causal role for combinatorial effects arising from the cont...

Alternative Titles

Full title

Synergistic Interactions between Drosophila Orthologues of Genes Spanned by De Novo Human CNVs Support Multiple-Hit Models of Autism

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1685141274

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1685141274

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1004998

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