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The N-terminus of murine leukaemia virus p12 protein is required for mature core stability

The N-terminus of murine leukaemia virus p12 protein is required for mature core stability

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1685245016

The N-terminus of murine leukaemia virus p12 protein is required for mature core stability

About this item

Full title

The N-terminus of murine leukaemia virus p12 protein is required for mature core stability

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2014-10, Vol.10 (10), p.e1004474-e1004474

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The murine leukaemia virus (MLV) gag gene encodes a small protein called p12 that is essential for the early steps of viral replication. The N- and C-terminal regions of p12 are sequentially acting domains, both required for p12 function. Defects in the C-terminal domain can be overcome by introducing a chromatin binding motif into the protein. How...

Alternative Titles

Full title

The N-terminus of murine leukaemia virus p12 protein is required for mature core stability

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1685245016

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1685245016

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1004474

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