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IFIT1 Differentially Interferes with Translation and Replication of Alphavirus Genomes and Promotes...

IFIT1 Differentially Interferes with Translation and Replication of Alphavirus Genomes and Promotes...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1685369117

IFIT1 Differentially Interferes with Translation and Replication of Alphavirus Genomes and Promotes Induction of Type I Interferon

About this item

Full title

IFIT1 Differentially Interferes with Translation and Replication of Alphavirus Genomes and Promotes Induction of Type I Interferon

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2015-04, Vol.11 (4), p.e1004863-e1004863

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Alphaviruses are a group of widely distributed human and animal pathogens. It is well established that their replication is sensitive to type I IFN treatment, but the mechanism of IFN inhibitory function remains poorly understood. Using a new experimental system, we demonstrate that in the presence of IFN-β, activation of interferon-stimulated gene...

Alternative Titles

Full title

IFIT1 Differentially Interferes with Translation and Replication of Alphavirus Genomes and Promotes Induction of Type I Interferon

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1685369117

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1685369117

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1004863

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