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Brugia malayi microfilariae induce a regulatory monocyte/macrophage phenotype that suppresses innate...

Brugia malayi microfilariae induce a regulatory monocyte/macrophage phenotype that suppresses innate...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1685536308

Brugia malayi microfilariae induce a regulatory monocyte/macrophage phenotype that suppresses innate and adaptive immune responses

About this item

Full title

Brugia malayi microfilariae induce a regulatory monocyte/macrophage phenotype that suppresses innate and adaptive immune responses

Publisher

United States: Public Library of Science

Journal title

PLoS neglected tropical diseases, 2014-10, Vol.8 (10), p.e3206-e3206

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Monocytes and macrophages contribute to the dysfunction of immune responses in human filariasis. During patent infection monocytes encounter microfilariae in the blood, an event that occurs in asymptomatically infected filariasis patients that are immunologically hyporeactive.
To determine whether blood microfilariae directly act on blood monocy...

Alternative Titles

Full title

Brugia malayi microfilariae induce a regulatory monocyte/macrophage phenotype that suppresses innate and adaptive immune responses

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1685536308

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1685536308

Other Identifiers

ISSN

1935-2735,1935-2727

E-ISSN

1935-2735

DOI

10.1371/journal.pntd.0003206

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