Effective Optimization of Antibody Affinity by Phage Display Integrated with High-Throughput DNA Syn...
Effective Optimization of Antibody Affinity by Phage Display Integrated with High-Throughput DNA Synthesis and Sequencing Technologies
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Full title
Author / Creator
Hu, Dongmei , Hu, Siyi , Wan, Wen , Xu, Man , Du, Ruikai , Zhao, Wei , Gao, Xiaolian , Liu, Jing , Liu, Haiyan and Hong, Jiong
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Phage display technology has been widely used for antibody affinity maturation for decades. The limited library sequence diversity together with excessive redundancy and labour-consuming procedure for candidate identification are two major obstacles to widespread adoption of this technology. We hereby describe a novel library generation and screeni...
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Full title
Effective Optimization of Antibody Affinity by Phage Display Integrated with High-Throughput DNA Synthesis and Sequencing Technologies
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Author / Creator
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Record Identifier
TN_cdi_plos_journals_1686215129
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1686215129
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0129125
