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Hyperglycemia and Diabetes Downregulate the Functional Expression of TRPV4 Channels in Retinal Micro...

Hyperglycemia and Diabetes Downregulate the Functional Expression of TRPV4 Channels in Retinal Micro...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1686215157

Hyperglycemia and Diabetes Downregulate the Functional Expression of TRPV4 Channels in Retinal Microvascular Endothelium

About this item

Full title

Hyperglycemia and Diabetes Downregulate the Functional Expression of TRPV4 Channels in Retinal Microvascular Endothelium

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-06, Vol.10 (6), p.e0128359-e0128359

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Retinal endothelial cell dysfunction is believed to play a key role in the etiology and pathogenesis of diabetic retinopathy. Numerous studies have shown that TRPV4 channels are critically involved in maintaining normal endothelial cell function. In the current paper, we demonstrate that TRPV4 is functionally expressed in the endothelium of the ret...

Alternative Titles

Full title

Hyperglycemia and Diabetes Downregulate the Functional Expression of TRPV4 Channels in Retinal Microvascular Endothelium

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1686215157

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1686215157

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0128359

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