Hepatic Progenitor Cells Contribute to the Progression of 2-Acetylaminofluorene/Carbon Tetrachloride...
Hepatic Progenitor Cells Contribute to the Progression of 2-Acetylaminofluorene/Carbon Tetrachloride-Induced Cirrhosis via the Non-Canonical Wnt Pathway
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Author / Creator
Chen, Jiamei , Zhang, Xiao , Xu, Ying , Li, Xuewei , Ren, Shuang , Zhou, Yaning , Duan, Yuyou , Zern, Mark , Zhang, Hua , Chen, Gaofeng , Liu, Chenghai , Mu, Yongping and Liu, Ping
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Contents
Hepatic progenitor cells (HPCs) appear to play an important role in chronic liver injury. In this study, cirrhosis was induced in F-344 rats (n = 32) via subcutaneous injection of 50% carbon tetrachloride (CCl4) twice a week for 8 weeks. Then, 30% CCl4 was administered in conjunction with intragastric 2-acetylaminofluorine (2-AAF) for 4 weeks to in...
Alternative Titles
Full title
Hepatic Progenitor Cells Contribute to the Progression of 2-Acetylaminofluorene/Carbon Tetrachloride-Induced Cirrhosis via the Non-Canonical Wnt Pathway
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TN_cdi_plos_journals_1689846062
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1689846062
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0130310
