Generation of Multicellular Tumor Spheroids with Microwell-Based Agarose Scaffolds for Drug Testing
Generation of Multicellular Tumor Spheroids with Microwell-Based Agarose Scaffolds for Drug Testing
About this item
Full title
Author / Creator
Gong, Xue , Lin, Chao , Cheng, Jian , Su, Jiansheng , Zhao, Hang , Liu, Tianlin , Wen, Xuejun and Zhao, Peng
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Three dimensional multicellular aggregate, also referred to as cell spheroid or microtissue, is an indispensable tool for in vitro evaluating antitumor activity and drug efficacy. Compared with classical cellular monolayer, multicellular tumor spheroid (MCTS) offers a more rational platform to predict in vivo drug efficacy and toxicity. Nevertheles...
Alternative Titles
Full title
Generation of Multicellular Tumor Spheroids with Microwell-Based Agarose Scaffolds for Drug Testing
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1689992595
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1689992595
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0130348
