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Englerin A Agonizes the TRPC4/C5 Cation Channels to Inhibit Tumor Cell Line Proliferation

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Englerin A Agonizes the TRPC4/C5 Cation Channels to Inhibit Tumor Cell Line Proliferation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1690399868

Englerin A Agonizes the TRPC4/C5 Cation Channels to Inhibit Tumor Cell Line Proliferation

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United States: Public Library of Science

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Englerin A is a structurally unique natural product reported to selectively inhibit growth of renal cell carcinoma cell lines. A large scale phenotypic cell profiling experiment (CLiP) of englerin A on ¬over 500 well characterized cancer cell lines showed that englerin A inhibits growth of a subset of tumor cell lines from many lineages, not just r...

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Englerin A Agonizes the TRPC4/C5 Cation Channels to Inhibit Tumor Cell Line Proliferation

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TN_cdi_plos_journals_1690399868

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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1690399868

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ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0127498

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