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Mutations in the 5' NTR and the Non-Structural Protein 3A of the Coxsackievirus B3 Selectively Atten...

Mutations in the 5' NTR and the Non-Structural Protein 3A of the Coxsackievirus B3 Selectively Atten...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1690399971

Mutations in the 5' NTR and the Non-Structural Protein 3A of the Coxsackievirus B3 Selectively Attenuate Myocarditogenicity

About this item

Full title

Mutations in the 5' NTR and the Non-Structural Protein 3A of the Coxsackievirus B3 Selectively Attenuate Myocarditogenicity

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-06, Vol.10 (6), p.e0131052-e0131052

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The 5' non-translated region (NTR) is an important molecular determinant that controls replication and virulence of coxsackievirus B (CVB)3. Previous studies have reported many nucleotide (nt) sequence differences in the Nancy strain of the virus, including changes in the 5' NTR with varying degrees of disease severity. In our studies of CVB3-induc...

Alternative Titles

Full title

Mutations in the 5' NTR and the Non-Structural Protein 3A of the Coxsackievirus B3 Selectively Attenuate Myocarditogenicity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1690399971

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1690399971

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0131052

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