Structural and Functional Analysis of Human HtrA3 Protease and Its Subdomains
Structural and Functional Analysis of Human HtrA3 Protease and Its Subdomains
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Human HtrA3 protease, which induces mitochondria-mediated apoptosis, can be a tumor suppressor and a potential therapeutic target in the treatment of cancer. However, there is little information about its structure and biochemical properties. HtrA3 is composed of an N-terminal domain not required for proteolytic activity, a central serine protease...
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Structural and Functional Analysis of Human HtrA3 Protease and Its Subdomains
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TN_cdi_plos_journals_1691274590
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1691274590
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0131142
