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Expression of Lectin-Like Transcript 1, the Ligand for CD161, in Rheumatoid Arthritis

Expression of Lectin-Like Transcript 1, the Ligand for CD161, in Rheumatoid Arthritis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1694530478

Expression of Lectin-Like Transcript 1, the Ligand for CD161, in Rheumatoid Arthritis

About this item

Full title

Expression of Lectin-Like Transcript 1, the Ligand for CD161, in Rheumatoid Arthritis

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-07, Vol.10 (7), p.e0132436-e0132436

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Precursor Th17 lineage cells expressing CD161 are implicated in Rheumatoid Arthritis (RA) pathogenesis. CD4+CD161+ T-cells accumulate in RA joints and may acquire a non classical Th1 phenotype. The endogenous ligand for CD161 is lectin-like transcript 1 (LLT1). CD161/LLT1 ligation may co-stimulate T-cell IFN-γ production. We investigated the presen...

Alternative Titles

Full title

Expression of Lectin-Like Transcript 1, the Ligand for CD161, in Rheumatoid Arthritis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1694530478

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1694530478

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0132436

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