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Lymphangioleiomyomatosis Biomarkers Linked to Lung Metastatic Potential and Cell Stemness

Lymphangioleiomyomatosis Biomarkers Linked to Lung Metastatic Potential and Cell Stemness

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1695996816

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Lymphangioleiomyomatosis (LAM) is a rare lung-metastasizing neoplasm caused by the proliferation of smooth muscle-like cells that commonly carry loss-of-function mutations in either the tuberous sclerosis complex 1 or 2 (TSC1 or TSC2) genes. While allosteric inhibition of the mechanistic target of rapamycin (mTOR) has shown substantial clinical ben...

Alternative Titles

Full title

Lymphangioleiomyomatosis Biomarkers Linked to Lung Metastatic Potential and Cell Stemness

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1695996816

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1695996816

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0132546

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