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In Vivo Senescence in the Sbds-Deficient Murine Pancreas: Cell-Type Specific Consequences of Transla...

In Vivo Senescence in the Sbds-Deficient Murine Pancreas: Cell-Type Specific Consequences of Transla...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1696855928

In Vivo Senescence in the Sbds-Deficient Murine Pancreas: Cell-Type Specific Consequences of Translation Insufficiency

About this item

Full title

In Vivo Senescence in the Sbds-Deficient Murine Pancreas: Cell-Type Specific Consequences of Translation Insufficiency

Publisher

United States: Public Library of Science

Journal title

PLoS genetics, 2015-06, Vol.11 (6), p.e1005288-e1005288

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Genetic models of ribosome dysfunction show selective organ failure, highlighting a gap in our understanding of cell-type specific responses to translation insufficiency. Translation defects underlie a growing list of inherited and acquired cancer-predisposition syndromes referred to as ribosomopathies. We sought to identify molecular mechanisms un...

Alternative Titles

Full title

In Vivo Senescence in the Sbds-Deficient Murine Pancreas: Cell-Type Specific Consequences of Translation Insufficiency

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1696855928

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1696855928

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1005288

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