Development of Membrane-Bound GM-CSF and IL-18 as an Effective Tumor Vaccine
Development of Membrane-Bound GM-CSF and IL-18 as an Effective Tumor Vaccine
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
The development of effective adjuvant is the key factor to boost the immunogenicity of tumor cells as a tumor vaccine. In this study, we expressed membrane-bound granulocyte-macrophage colony-stimulating factor (GM-CSF) and interleukin-18 (IL-18) as adjuvants in tumor cells to stimulate immune response. B7 transmembrane domain fused GM-CSF and IL-1...
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Full title
Development of Membrane-Bound GM-CSF and IL-18 as an Effective Tumor Vaccine
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TN_cdi_plos_journals_1697016134
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1697016134
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0133470
