A Chimeric HIV-1 gp120 Fused with Vaccinia Virus 14K (A27) Protein as an HIV Immunogen
A Chimeric HIV-1 gp120 Fused with Vaccinia Virus 14K (A27) Protein as an HIV Immunogen
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
In the HIV vaccine field, there is a need to produce highly immunogenic forms of the Env protein with the capacity to trigger broad B and T-cell responses. Here, we report the generation and characterization of a chimeric HIV-1 gp120 protein (termed gp120-14K) by fusing gp120 from clade B with the vaccinia virus (VACV) 14K oligomeric protein (deriv...
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Full title
A Chimeric HIV-1 gp120 Fused with Vaccinia Virus 14K (A27) Protein as an HIV Immunogen
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TN_cdi_plos_journals_1698611571
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1698611571
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0133595