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The Demethylase Activity of FTO (Fat Mass and Obesity Associated Protein) Is Required for Preadipocy...

The Demethylase Activity of FTO (Fat Mass and Obesity Associated Protein) Is Required for Preadipocy...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1699513427

The Demethylase Activity of FTO (Fat Mass and Obesity Associated Protein) Is Required for Preadipocyte Differentiation

About this item

Full title

The Demethylase Activity of FTO (Fat Mass and Obesity Associated Protein) Is Required for Preadipocyte Differentiation

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-07, Vol.10 (7), p.e0133788-e0133788

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

FTO (fat mass and obesity associated gene) was genetically identified to be associated with body mass index (BMI), presumably through functional regulation of energy homeostasis. However, the cellular and molecular mechanisms by which FTO functions remain largely unknown. Using 3T3-L1 preadipocyte as a model to study the role of FTO in adipogenesis...

Alternative Titles

Full title

The Demethylase Activity of FTO (Fat Mass and Obesity Associated Protein) Is Required for Preadipocyte Differentiation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1699513427

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1699513427

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0133788

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