Tolerance and Cross-Tolerance following Toll-Like Receptor (TLR)-4 and -9 Activation Are Mediated by...
Tolerance and Cross-Tolerance following Toll-Like Receptor (TLR)-4 and -9 Activation Are Mediated by IRAK-M and Modulated by IL-7 in Murine Splenocytes
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Immune suppression during critical illness predisposes to serious infections. We sought to determine the mechanisms regulating tolerance and cross-tolerance to common pro-inflammatory danger signals in a model that recapitulates the intact in vivo immune response.
Flt3-expanded splenocytes obtained from wild-type or matching IRAK-M knockout (IRA...
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Full title
Tolerance and Cross-Tolerance following Toll-Like Receptor (TLR)-4 and -9 Activation Are Mediated by IRAK-M and Modulated by IL-7 in Murine Splenocytes
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TN_cdi_plos_journals_1699513463
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1699513463
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0132921
