Robustness of Next Generation Sequencing on Older Formalin-Fixed Paraffin-Embedded Tissue
Robustness of Next Generation Sequencing on Older Formalin-Fixed Paraffin-Embedded Tissue
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Author / Creator
Carrick, Danielle Mercatante , Mehaffey, Michele G , Sachs, Michael C , Altekruse, Sean , Camalier, Corinne , Chuaqui, Rodrigo , Cozen, Wendy , Das, Biswajit , Hernandez, Brenda Y , Lih, Chih-Jian , Lynch, Charles F , Makhlouf, Hala , McGregor, Paul , McShane, Lisa M , Phillips Rohan, JoyAnn , Walsh, William D , Williams, Paul M , Gillanders, Elizabeth M , Mechanic, Leah E and Schully, Sheri D
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Next Generation Sequencing (NGS) technologies are used to detect somatic mutations in tumors and study germ line variation. Most NGS studies use DNA isolated from whole blood or fresh frozen tissue. However, formalin-fixed paraffin-embedded (FFPE) tissues are one of the most widely available clinical specimens. Their potential utility as a source o...
Alternative Titles
Full title
Robustness of Next Generation Sequencing on Older Formalin-Fixed Paraffin-Embedded Tissue
Authors, Artists and Contributors
Author / Creator
Mehaffey, Michele G
Sachs, Michael C
Altekruse, Sean
Camalier, Corinne
Chuaqui, Rodrigo
Cozen, Wendy
Das, Biswajit
Hernandez, Brenda Y
Lih, Chih-Jian
Lynch, Charles F
Makhlouf, Hala
McGregor, Paul
McShane, Lisa M
Phillips Rohan, JoyAnn
Walsh, William D
Williams, Paul M
Gillanders, Elizabeth M
Mechanic, Leah E
Schully, Sheri D
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Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1700107542
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1700107542
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0127353