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Robustness of Next Generation Sequencing on Older Formalin-Fixed Paraffin-Embedded Tissue

Robustness of Next Generation Sequencing on Older Formalin-Fixed Paraffin-Embedded Tissue

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1700107542

Robustness of Next Generation Sequencing on Older Formalin-Fixed Paraffin-Embedded Tissue

About this item

Full title

Robustness of Next Generation Sequencing on Older Formalin-Fixed Paraffin-Embedded Tissue

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-07, Vol.10 (7), p.e0127353-e0127353

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Next Generation Sequencing (NGS) technologies are used to detect somatic mutations in tumors and study germ line variation. Most NGS studies use DNA isolated from whole blood or fresh frozen tissue. However, formalin-fixed paraffin-embedded (FFPE) tissues are one of the most widely available clinical specimens. Their potential utility as a source o...

Alternative Titles

Full title

Robustness of Next Generation Sequencing on Older Formalin-Fixed Paraffin-Embedded Tissue

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1700107542

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1700107542

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0127353

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