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Bortezomib Plus Continuous B Cell Depletion Results in Sustained Plasma Cell Depletion and Ameliorat...

Bortezomib Plus Continuous B Cell Depletion Results in Sustained Plasma Cell Depletion and Ameliorat...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1702213278

Bortezomib Plus Continuous B Cell Depletion Results in Sustained Plasma Cell Depletion and Amelioration of Lupus Nephritis in NZB/W F1 Mice

About this item

Full title

Bortezomib Plus Continuous B Cell Depletion Results in Sustained Plasma Cell Depletion and Amelioration of Lupus Nephritis in NZB/W F1 Mice

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-08, Vol.10 (8), p.e0135081-e0135081

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

NZB/W F1 mice were treated with: 1) anti-CD20, 2) anti-CD20 plus bortezomib, 3) anti-CD20 plus anti-LFA-1/anti-VLA-4 blocking antibodies, 4) anti-CD20 plus bortezomib and anti-LFA-1/anti-VLA4 blocking antibodies. Short- and long-lived plasma cells including autoreactive cells in the bone marrow and spleen were enumerated by flow cytometry and ELISP...

Alternative Titles

Full title

Bortezomib Plus Continuous B Cell Depletion Results in Sustained Plasma Cell Depletion and Amelioration of Lupus Nephritis in NZB/W F1 Mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1702213278

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1702213278

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0135081

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