Mycolactone-Dependent Depletion of Endothelial Cell Thrombomodulin Is Strongly Associated with Fibri...
Mycolactone-Dependent Depletion of Endothelial Cell Thrombomodulin Is Strongly Associated with Fibrin Deposition in Buruli Ulcer Lesions
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United States: Public Library of Science
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English
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United States: Public Library of Science
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A well-known histopathological feature of diseased skin in Buruli ulcer (BU) is coagulative necrosis caused by the Mycobacterium ulcerans macrolide exotoxin mycolactone. Since the underlying mechanism is not known, we have investigated the effect of mycolactone on endothelial cells, focussing on the expression of surface anticoagulant molecules inv...
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Mycolactone-Dependent Depletion of Endothelial Cell Thrombomodulin Is Strongly Associated with Fibrin Deposition in Buruli Ulcer Lesions
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TN_cdi_plos_journals_1705069868
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1705069868
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1553-7374,1553-7366
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1553-7374
DOI
10.1371/journal.ppat.1005011