Overexpression of Both ERG11 and ABC2 Genes Might Be Responsible for Itraconazole Resistance in Clin...
Overexpression of Both ERG11 and ABC2 Genes Might Be Responsible for Itraconazole Resistance in Clinical Isolates of Candida krusei
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Author / Creator
He, Xiaoyuan , Zhao, Mingfeng , Chen, Jinyan , Wu, Rimao , Zhang, Jianlei , Cui, Rui , Jiang, Yanyu , Chen, Jie , Cao, Xiaoli , Xing, Yi , Zhang, Yuchen , Meng, Juanxia , Deng, Qi and Sui, Tao
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
To study the main molecular mechanisms responsible for itraconazole resistance in clinical isolates of Candida krusei.
The 14α-demethylases encoded by ERG11 gene in the 16 C.krusei clinical isolates were amplified by polymerase chain reaction (PCR), and their nucleotide sequences were determined to detect point mutations. Meanwhile, ERG11 and ef...
Alternative Titles
Full title
Overexpression of Both ERG11 and ABC2 Genes Might Be Responsible for Itraconazole Resistance in Clinical Isolates of Candida krusei
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Record Identifier
TN_cdi_plos_journals_1708482387
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1708482387
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0136185
