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Deletion of RBPJK in Mesenchymal Stem Cells Enhances Osteogenic Activity by Up-Regulation of BMP Sig...

Deletion of RBPJK in Mesenchymal Stem Cells Enhances Osteogenic Activity by Up-Regulation of BMP Sig...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1708482389

Deletion of RBPJK in Mesenchymal Stem Cells Enhances Osteogenic Activity by Up-Regulation of BMP Signaling

About this item

Full title

Deletion of RBPJK in Mesenchymal Stem Cells Enhances Osteogenic Activity by Up-Regulation of BMP Signaling

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-08, Vol.10 (8), p.e0135971-e0135971

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Recently we have demonstrated the importance of RBPjk-dependent Notch signaling in the regulation of mesenchymal stem cell (MSC) differentiation during skeletogenesis both in vivo and in vitro. Here we further performed RBPJK loss-of-function experiments to demonstrate for the first time that RBPJK deficient MSC shows enhanced differentiation and o...

Alternative Titles

Full title

Deletion of RBPJK in Mesenchymal Stem Cells Enhances Osteogenic Activity by Up-Regulation of BMP Signaling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1708482389

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1708482389

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0135971

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