Three-Dimensional Environment Sustains Hematopoietic Stem Cell Differentiation into Platelet-Produci...
Three-Dimensional Environment Sustains Hematopoietic Stem Cell Differentiation into Platelet-Producing Megakaryocytes
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Hematopoietic stem cells (HSC) differentiate into megakaryocytes (MK), whose function is to release platelets. Attempts to improve in vitro platelet production have been hampered by the low amplification of MK. Providing HSC with an optimal three-dimensional (3D) architecture may favor MK differentiation by mimicking some crucial functions of the b...
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Full title
Three-Dimensional Environment Sustains Hematopoietic Stem Cell Differentiation into Platelet-Producing Megakaryocytes
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TN_cdi_plos_journals_1708482855
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1708482855
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0136652
