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Local IL-17 Production Exerts a Protective Role in Murine Experimental Glomerulonephritis

Local IL-17 Production Exerts a Protective Role in Murine Experimental Glomerulonephritis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1708482884

Local IL-17 Production Exerts a Protective Role in Murine Experimental Glomerulonephritis

About this item

Full title

Local IL-17 Production Exerts a Protective Role in Murine Experimental Glomerulonephritis

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-08, Vol.10 (8), p.e0136238

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

IL-17 is a pro-inflammatory cytokine implicated in the pathogenesis of glomerulonephritis and IL-17 deficient mice are protected from nephrotoxic nephritis. However, a regulatory role for IL-17 has recently emerged. We describe a novel protective function for IL-17 in the kidney. Bone marrow chimeras were created using wild-type and IL-17 deficient...

Alternative Titles

Full title

Local IL-17 Production Exerts a Protective Role in Murine Experimental Glomerulonephritis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1708482884

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1708482884

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0136238

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