New Mechanisms of Flucytosine Resistance in C. glabrata Unveiled by a Chemogenomics Analysis in S. c...
New Mechanisms of Flucytosine Resistance in C. glabrata Unveiled by a Chemogenomics Analysis in S. cerevisiae
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United States: Public Library of Science
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English
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United States: Public Library of Science
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5-Flucytosine is currently used as an antifungal drug in combination therapy, but fungal pathogens are rapidly able to develop resistance against this drug, compromising its therapeutic action. The understanding of the underlying resistance mechanisms is crucial to deal with this problem. In this work, the S. cerevisiae deletion mutant collection w...
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New Mechanisms of Flucytosine Resistance in C. glabrata Unveiled by a Chemogenomics Analysis in S. cerevisiae
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TN_cdi_plos_journals_1708528915
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1708528915
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1932-6203
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1932-6203
DOI
10.1371/journal.pone.0135110