Generation of SNCA Cell Models Using Zinc Finger Nuclease (ZFN) Technology for Efficient High-Throug...
Generation of SNCA Cell Models Using Zinc Finger Nuclease (ZFN) Technology for Efficient High-Throughput Drug Screening
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Parkinson's disease (PD) is a progressive neurodegenerative disorder caused by loss of dopaminergic neurons of the substantia nigra. The hallmark of PD is the appearance of neuronal protein aggregations known as Lewy bodies and Lewy neurites, of which α-synuclein forms a major component. Familial PD is rare and is associated with missense mutations...
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Generation of SNCA Cell Models Using Zinc Finger Nuclease (ZFN) Technology for Efficient High-Throughput Drug Screening
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TN_cdi_plos_journals_1708566678
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1708566678
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0136930
