PKC and AKT Modulate cGMP/PKG Signaling Pathway on Platelet Aggregation in Experimental Sepsis
PKC and AKT Modulate cGMP/PKG Signaling Pathway on Platelet Aggregation in Experimental Sepsis
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Sepsis severity has been positively correlated with platelet dysfunction, which may be due to elevations in nitric oxide (NO) and cGMP levels. Protein kinase C, Src kinases, PI3K and AKT modulate platelet activity in physiological conditions, but no studies evaluated the role of these enzymes in platelet aggregation in sepsis. In the present study...
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PKC and AKT Modulate cGMP/PKG Signaling Pathway on Platelet Aggregation in Experimental Sepsis
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TN_cdi_plos_journals_1719285719
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1719285719
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0137901
