Cryptococcus neoformans Infection in Mice Lacking Type I Interferon Signaling Leads to Increased Fun...
Cryptococcus neoformans Infection in Mice Lacking Type I Interferon Signaling Leads to Increased Fungal Clearance and IL-4-Dependent Mucin Production in the Lungs
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Type I interferons (IFNs) are secreted by many cell types upon stimulation via pattern recognition receptors and bind to IFN-α/β receptor (IFNAR), which is composed of IFNAR1 and IFNAR2. Although type I IFNs are well known as anti-viral cytokines, limited information is available on their role during fungal infection. In the present study, we addre...
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Cryptococcus neoformans Infection in Mice Lacking Type I Interferon Signaling Leads to Increased Fungal Clearance and IL-4-Dependent Mucin Production in the Lungs
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TN_cdi_plos_journals_1719288673
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1719288673
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1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0138291