Gpr116 Receptor Regulates Distinctive Functions in Pneumocytes and Vascular Endothelium
Gpr116 Receptor Regulates Distinctive Functions in Pneumocytes and Vascular Endothelium
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Author / Creator
Niaudet, Colin , Hofmann, Jennifer J. , Mäe, Maarja A. , Jung, Bongnam , Gaengel, Konstantin , Vanlandewijck, Michael , Ekvärn, Elisabet , Salvado, M. Dolores , Mehlem, Annika , Al Sayegh, Sahar , He, Liqun , Lebouvier, Thibaud , Castro-Freire, Marco , Katayama, Kan , Hultenby, Kjell , Moessinger, Christine , Tannenberg, Philip , Cunha, Sara , Pietras, Kristian , Laviña, Bàrbara , Hong, JongWook , Berg, Tove , Betsholtz, Christer , Faculty of Medicine , Medicinska fakulteten , Lund University , Avdelningen för translationell cancerforskning , Institutionen för laboratoriemedicin , Department of Laboratory Medicine , Division of Translational Cancer Research and Lunds universitet
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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More information
Scope and Contents
Contents
Despite its known expression in both the vascular endothelium and the lung epithelium, until recently the physiological role of the adhesion receptor Gpr116/ADGRF5 has remained elusive. We generated a new mouse model of constitutive Gpr116 inactivation, with a large genetic deletion encompassing exon 4 to exon 21 of the Gpr116 gene. This model allo...
Alternative Titles
Full title
Gpr116 Receptor Regulates Distinctive Functions in Pneumocytes and Vascular Endothelium
Authors, Artists and Contributors
Author / Creator
Hofmann, Jennifer J.
Mäe, Maarja A.
Jung, Bongnam
Gaengel, Konstantin
Vanlandewijck, Michael
Ekvärn, Elisabet
Salvado, M. Dolores
Mehlem, Annika
Al Sayegh, Sahar
He, Liqun
Lebouvier, Thibaud
Castro-Freire, Marco
Katayama, Kan
Hultenby, Kjell
Moessinger, Christine
Tannenberg, Philip
Cunha, Sara
Pietras, Kristian
Laviña, Bàrbara
Hong, JongWook
Berg, Tove
Betsholtz, Christer
Faculty of Medicine
Medicinska fakulteten
Lund University
Avdelningen för translationell cancerforskning
Institutionen för laboratoriemedicin
Department of Laboratory Medicine
Division of Translational Cancer Research
Lunds universitet
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Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1719292378
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1719292378
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0137949
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