Clusterin Seals the Ocular Surface Barrier in Mouse Dry Eye
Clusterin Seals the Ocular Surface Barrier in Mouse Dry Eye
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Author / Creator
Bauskar, Aditi , Mack, Wendy J. , Mauris, Jerome , Argüeso, Pablo , Heur, Martin , Nagel, Barbara A. , Kolar, Grant R. , Gleave, Martin E. , Nakamura, Takahiro , Kinoshita, Shigeru , Moradian-Oldak, Janet , Panjwani, Noorjahan , Pflugfelder, Stephen C. , Wilson, Mark R. , Fini, M. Elizabeth and Jeong, Shinwu
Publisher
United States: Public Library of Science (PLoS)
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Language
English
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Publisher
United States: Public Library of Science (PLoS)
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Scope and Contents
Contents
Dry eye is a common disorder caused by inadequate hydration of the ocular surface that results in disruption of barrier function. The homeostatic protein clusterin (CLU) is prominent at fluid-tissue interfaces throughout the body. CLU levels are reduced at the ocular surface in human inflammatory disorders that manifest as severe dry eye, as well a...
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Full title
Clusterin Seals the Ocular Surface Barrier in Mouse Dry Eye
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Record Identifier
TN_cdi_plos_journals_1719304938
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1719304938
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0138958
