Nasal Administration of Cholera Toxin as a Mucosal Adjuvant Damages the Olfactory System in Mice
Nasal Administration of Cholera Toxin as a Mucosal Adjuvant Damages the Olfactory System in Mice
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Cholera toxin (CT) induces severe diarrhea in humans but acts as an adjuvant to enhance immune responses to vaccines when administered orally. Nasally administered CT also acts as an adjuvant, but CT and CT derivatives, including the B subunit of CT (CTB), are taken up from the olfactory epithelium and transported to the olfactory bulbs and therefo...
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Full title
Nasal Administration of Cholera Toxin as a Mucosal Adjuvant Damages the Olfactory System in Mice
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TN_cdi_plos_journals_1719342555
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1719342555
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0139368
