Phosphorylation of Threonine 794 on Tie1 by Rac1/PAK1 Reveals a Novel Angiogenesis Regulatory Pathwa...
Phosphorylation of Threonine 794 on Tie1 by Rac1/PAK1 Reveals a Novel Angiogenesis Regulatory Pathway
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United States: Public Library of Science
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English
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United States: Public Library of Science
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The endothelial receptor tyrosine kinase (RTK) Tie1 was discovered over 20 years ago, yet its precise function and mode of action remain enigmatic. To shed light on Tie1's role in endothelial cell biology, we investigated a potential threonine phosphorylation site within the juxtamembrane domain of Tie1. Expression of a non-phosphorylatable mutant...
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Phosphorylation of Threonine 794 on Tie1 by Rac1/PAK1 Reveals a Novel Angiogenesis Regulatory Pathway
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TN_cdi_plos_journals_1719374568
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1719374568
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0139614
