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Changes in Brain Metallome/Metabolome Pattern due to a Single i.v. Injection of Manganese in Rats

Changes in Brain Metallome/Metabolome Pattern due to a Single i.v. Injection of Manganese in Rats

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1720074519

Changes in Brain Metallome/Metabolome Pattern due to a Single i.v. Injection of Manganese in Rats

About this item

Full title

Changes in Brain Metallome/Metabolome Pattern due to a Single i.v. Injection of Manganese in Rats

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-09, Vol.10 (9), p.e0138270-e0138270

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Exposure to high concentrations of Manganese (Mn) is known to potentially induce an accumulation in the brain, leading to a Parkinson related disease, called manganism. Versatile mechanisms of Mn-induced brain injury are discussed, with inactivation of mitochondrial defense against oxidative stress being a major one. So far, studies indicate that t...

Alternative Titles

Full title

Changes in Brain Metallome/Metabolome Pattern due to a Single i.v. Injection of Manganese in Rats

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1720074519

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1720074519

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0138270

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