Effects of Adenovirus Type 5 E1A Isoforms on Viral Replication in Arrested Human Cells
Effects of Adenovirus Type 5 E1A Isoforms on Viral Replication in Arrested Human Cells
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Human adenovirus has evolved to infect and replicate in terminally differentiated human epithelial cells, predominantly those within the airway, the gut, or the eye. To overcome the block to viral DNA replication present in these cells, the virus expresses the Early 1A proteins (E1A). These immediate early proteins drive cells into S-phase and indu...
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Effects of Adenovirus Type 5 E1A Isoforms on Viral Replication in Arrested Human Cells
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TN_cdi_plos_journals_1720192542
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1720192542
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0140124
